SDTM to ADaM to TLF Pipeline TRACEABILITY

Recreation of the clinical Biometrics (statistical programming) chain: collected SDTM domains are derived into analysis-ready ADaM datasets, which are aggregated into the TLF outputs of a Clinical Study Report. The data is generated by a deterministic, seeded synthetic engine (SDTM DM / EX / AE), then ADSL and ADAE are derived in the browser with the real SAFFL and TRTEMFL logic shown, and every table count is computed from the ADaM, not hard-coded, so the numbers reconcile and each one traces back to source. Synthetic study, no real subjects.